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gene therapy treatments

Posted by gdp1943wls @gdp1943wls, Sep 14, 2017

are there any clinical trials for gene therapy treatments for h @ n cancers?

Interested in more discussions like this? Go to the Head and Neck Cancers group.

Not sure exactly what you are asking; Genomic tests are used to identify the specific genes in a cancer that are abnormal or are not working properly. In essence, this is like identifying the genetic signature or fingerprint of a particular cancer. Genomic testing is different from genetic testing. Genetic tests are typically used to determine whether a healthy individual has an inherited trait (gene) that predisposes them to developing cancer. Genomic tests evaluate the genes in a sample of diseased tissue (cancer) from a patient who has already been diagnosed with cancer. In this way, genes that have mutated, or have developed abnormal functions, are identified in addition to those that may have been inherited. There are numerous genomic trials in HENT cancer evaluating new targeted therapies directed at biomarkers encoded in the cancers DNA that are currently ongoing as well as FDA approved treatments.

Gene therapy which actually targets or alters an abnormal gene with is much more experimental: the NCI provides a list of open trials here https://clinicaltrials.gov/ct2/results?term=%22gene+therapy%22+OR+%22gene+transfer%22+OR+%22virus+delivery%22&cond=Cancer&cntry1=NA%3AUS&Search=Apply&recrs=a&age_v=&age=1&gndr=&type=&rslt=
Best
C

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