Ask the Expert: Question about HPV Status

Question: Does HPV status affect treatment and when should I be tested for HPV (I have throat cancer)?

Response: HPV testing is typically done during the initial pathologic evaluation of your tumor. It can be performed on the primary tumor site or in the lymph nodes.
One of the most active areas of research in our field is treatment deintensification in HPV-related oropharynx cancer. However, according to the latest National Cancer Center Network guidelines, HPV status does not change treatment recommendations, and any treatment deintensification or alteration of treatment based upon HPV status should be done in the context of a clinical trial.

Dr. Kang is an Assistant Professor in the Department of Otolaryngology – Head & Neck Surgery at The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute (OSUCCC – James) , specializing in the comprehensive management of benign and malignant head and neck tumors. Click the following links to learn more about Dr. Kang and the OSUCCC– James: https://cancer.osu.edu/find-a-doctor/search-physician-directory/stephen-y-kang and https://cancer.osu.edu/.

The Ask the Expert Guest Moderator is not intended to be a substitute for healthcare professional medical advice, diagnosis, or treatment. Speak to your healthcare provider about any questions you may have regarding your health.